How much are you willing to pay? A good hand produced watch will probably start around $5,000 and can go up well beyond that. Hardly any watch makers make the whole watch by hand anymore but the more you are willing to spend, the higher the amount of hand craftsmanship that you'll get. One company that does a lot of their watches the old fashioned way that I really like is Roland G. Murphy. They're American based and use the old artisan techniques. They also use vintage movements (that were handmade back in the day) in some of their watches. Check out
www.rgmwatches.com for more details.