It is always difficult to state any prices with regards to Prague hotels because a lot of their business is done through (online and offline) travel agents who buy the rooms in bulk at a discount rate and then pass on a certain percentage of that discount to their customers. Accordingly, depending on where you book, the room rates change. So tip number one:For the best prices for Prague hotels, always go through booking sites. They offer the best deals. (Better than the hotels themselves!)When it comes to luxury, there are several things to look out for: Do you want modern comforts or beautiful old rooms? City life or peace and quiet? I have heard that Hotel Angel, And the Yasmin Hotel are supposed to be good. The big chain hotels with all the mod cons are also all there - Holiday Inn, Hilton, Mövenpick, you name it, they have it. But for best results, I reccommend a search on such sites as
www.expedia.co.uk. Have a good look at what's on offer and maybe compare a few sites and I'm sure you'll be satisfied.